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Modulation Optics (Glen Cove, NY) manufactures Hoffman Modulation Contrast microscope components and systems for use in live cell imaging applications such as stem cell imaging, cancer study and embryo and sperm monitoring during in vitro fertilization procedures. The Hoffman Modulation Contrast technology, originally developed and patented by Robert Hoffman, has become the most widely used light microscopy contrast method for viewing colorless and transparent biological specimens.
Hoffman Modulation Contrast can be applied to most objective lenses including Olympus, Nikon, Zeiss, Leica, and high magnification imaging systems from Navitar. In fact, Olympus, Nikon, and Zeiss have historically been three of Modulation Optics’ largest customers. Modulation Optics offers HMC accessories.