Exponential growth and accelerated changes, the main characteristics of Industry 4.0, are determining Quality 4.0. Cyber-physical systems, the internet of things and systems, information and communications technology, new materials, big data, cloud and cognitive computing, augmented and virtual reality, artificial intelligence, machine learning, blockchain technology, 3D printing and many other technologies are making a significant impact on the process of creating products and services and therefore, their quality. People, processes and technologies—the three key elements of Quality 4.0—are combined to achieve operational excellence and improve overall performance and quality of products and services. All these advancements will affect the level of quality in a positive way.